Fractal dimension analysis reveals skeletal muscle disorganization in mdx mice
نویسندگان
چکیده
منابع مشابه
Collagen content does not alter the passive mechanical properties of fibrotic skeletal muscle in mdx mice.
Many skeletal muscle diseases are associated with progressive fibrosis leading to impaired muscle function. Collagen within the extracellular matrix is the primary structural protein providing a mechanical scaffold for cells within tissues. During fibrosis collagen not only increases in amount but also undergoes posttranslational changes that alter its organization that is thought to contribute...
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Disruptions in the use of skeletal muscle lead to muscle atrophy. After short periods of disuse, muscle atrophy is reversible, and even after prolonged periods of inactivity, myofiber degeneration is uncommon. The pathways that regulate atrophy, initiated either by peripheral nerve damage, immobilization, aging, catabolic steroids, or cancer cachexia, however, are poorly understood. Previously,...
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ژورنال
عنوان ژورنال: Biochemical and Biophysical Research Communications
سال: 2018
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2018.05.189